CD7 antibody (FITC)

Catalog No. ABIN1106542

This Mouse Monoclonal antibody specifically detects CD7 in FACS and IF. It exhibits reactivity toward Human.

Quick Overview for CD7 antibody (FITC) (ABIN1106542)

Target: CD7

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD7 antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: B-B7

Product Details anti-CD7 Antibody (FITC)

Specificity: Clone B-B7 recognizes a 40 kDa T cell and NK cell antigen.

Purification: Affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.

Target Details for CD7

Target: CD7

Alternative Name: CD7

Background: CD7 is the earliest antigen marker expressed in the T lineage, being found on T cell precursors in fetal liver and thorax prior to thymic colonization and in thymus and bone marrow. The function of CD7 antigen is unknown and the natural ligand for CD7 has not yet been identified. CD7 monoclonal antibodies co-stimulate T cell proliferation and induce second messengers, while soluble recombinant CD7 has been reported to inhibit antigen-specific proliferation and a mixed lymphocyte reaction. CD7 is a marker for pluripotential stem cell leukemias and T cell acute lymphocytic leukemia (T-ALL). The antigen is frequently lost on large cell T cell lymphomas. The CD7 antigen may also be expressed on myeloblastic leukemias.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41

Gene ID: 924

NCBI Accession: NP_006128

UniProt: P09564

Pathways: Cell-Cell Junction Organization