CEBPD antibody (N-Term)

Catalog No. ABIN1106666

The Rabbit Polyclonal anti-CEBPD antibody is suitable to detect CEBPD in samples from Human and Mouse. It has been validated for WB, IP and EIA.

Quick Overview for CEBPD antibody (N-Term) (ABIN1106666)

Target: CEBPD (CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEBPD antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Product Details anti-CEBPD Antibody

Binding Specificity: N-Term

Specificity: This antibody is specific for C/EBP delta protein. No cross-reactivity is observed with Mouse C/EBPalpha or C/EBPbeta.

Cross-Reactivity (Details): Species reactivity (expected):Human.
Species reactivity (tested):Mouse.

Purification: Immunoaffinity Chromatography

Immunogen: Recombinant protein corresponding to the amino terminus of Mouse C/EBP.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.83 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for CEBPD

Target: CEBPD (CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD))

Alternative Name: CEBPD

Background: C/EBP proteins are DNA-binding proteins that are important transcriptional activators in the regulation of genes involved in immune and inflammatory responses and may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Members of the C/EBP transcription factor family are related by a high degree of amino acid sequence identity to the basic leucine zipper DNA-binding domain and show distinct but overlapping patterns of tissue- and stage-restricted expression. Osada et al. identified the consensus binding site for the family as RTTGCGYAAY (R = A or G, and Y = C or T). Phosphorylation of C/EBPdelta may increase binding activity, whereas phosphorylation of the alpha and beta family members may decrease binding affinity. C/EBPdelta is a nuclear protein that binds DNA as a dimer and can form stable heterodimers with all other C/EBP family members.Synonyms: C/EBP delta, CCAAT/enhancer-binding protein delta, NF-IL6-beta, Nuclear factor NF-IL6-beta

Gene ID: 12609

NCBI Accession: NP_031705

UniProt: Q00322