The Mouse Monoclonal anti-SCGB1A1 antibody has been validated for WB, IHC (p), IHC (fro) and EIA. It is suitable to detect SCGB1A1 in samples from Human.
SCGB1A1
Reactivity: Rat
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
0.1 mg/mL
Buffer
PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store at 2 - 8 °C.
Target
SCGB1A1
(Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))
Alternative Name
Clara Cell Protein (CC16)
Background
Clara cell protein or urinary protein 1 is a homodimeric protein of 16 kD and is secreted predominantly by Clara cells in terminal bronchioles and from puberty on in the male urogenital tract. CC16 is formed by two chains, each with a molecular weight of 7.9 kD. CC16 occurs in very high concentrations in respiratory tract derived fluids such as sputum or bronchoalveolar lavage fluid. CC16 occurs also in urogenital secretions, such as amniotic fluid, urine and semen. The protein difusses passively into serum. CC16 behaves like an anti-cytokine by downregulating the production of IFN-gamma, IL-1 and TNF-alpha by stimulated leukocytes. Besides this, CC16 reduces the antiviral activity and the augmentation of phagocytosis induced by IFN-gamma.Synonyms: Urinary protein 1