C9 antibody

Catalog No. ABIN1106798

The Mouse Monoclonal anti-C9 antibody has been validated for WB, IHC (p), EIA, IHC (fro) and Func. It is suitable to detect C9 in samples from Human.

Quick Overview for C9 antibody (ABIN1106798)

Target: C9 (Complement Component C9 (C9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: X197

Product Details anti-C9 Antibody

Specificity: This antibody detects C9.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein G

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2 - 8 °C.

Target Details for C9

Target: C9 (Complement Component C9 (C9))

Alternative Name: Complement C9

Background: Human C9 is a soluble glycoprotein of 61 kD. It is the last component in the assembly of the membrane attack complex (MAC). When the complement is activated on target membranes, multiple copies of C9 bind to the C5b-8 complex and assemble the barrel-shaped pore which causes cell lysis. The conformation of C9 changes from globular to a tubular form. The binding of C9 to C5b-8 plays a key role in the function of C9.Synonyms: Complement 9, Complement component C9

Gene ID: 735

NCBI Accession: NP_001728

UniProt: P02748

Pathways: Complement System