Elastin antibody

Catalog No. ABIN1107083

The Mouse Monoclonal anti-Elastin antibody has been validated for IP and IHC (p). It is suitable to detect Elastin in samples from Human, Cow, Dog and Guinea Pig.

Quick Overview for Elastin antibody (ABIN1107083)

Target: Elastin (ELN)

Reactivity: Human, Cow, Dog, Guinea Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This Elastin antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IL-4

Product Details anti-Elastin Antibody

Specificity: This antibody reacts to Elastin.

Purification: Affinity chromatography

Immunogen: Bovine alpha-elastin

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Elastin

Target: Elastin (ELN)

Alternative Name: Elastin

Background: Elastin is a major structural protein of tissues such as aorta, which must expand rapidly and recover completely. Elastin chains are cross-linked together into an extensible 3D network. It is a molecular determinant of late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. Defects in elastin are a cause of autosomal dominant cutis laxa.Synonyms: ELN, Tropoelastin

Gene ID: 2006

NCBI Accession: NP_001075221

UniProt: P15502

Pathways: Regulation of Actin Filament Polymerization