GPM6A antibody
Quick Overview for GPM6A antibody (ABIN1107419)
Target
See all GPM6A AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody reacts with M6a.
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Cross-Reactivity (Details)
- Species reactivity (tested):Mouse
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Purification
- Protein G agarose
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Immunogen
- Mouse M6a expressing cells
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Isotype
- IgG2a
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store (in aliquots) at -20 °C.
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- GPM6A (Glycoprotein M6A (GPM6A))
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Alternative Name
- GPM6A
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Background
- M6 is a membrane glycoprotein that is abundantly expressed on central neurons in the CHS. Two distinct murine M6 cDNA (designated M6a and M6b) whose deduced amino acid sequences are remarkably similar to that of the major CNS myelin protein PLP/DM20 are known. PLP expression is limited to the white matter. M6a appears in post-mitotic neurons of the brain and spinal cord as early as embryonic day 10, and later in the hippocampus, cerebral cortex, and the granule cells of the cerebellum. In contrast, M6b is expressed at early embryonic stage in the ventricular zone of the spinal cord, and later during development in both neurons and glia.Synonyms: Neuronal membrane glycoprotein M6-a
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Gene ID
- 234267
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NCBI Accession
- NP_705809
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UniProt
- P35802
Target
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