Laminin gamma 1 antibody

Catalog No. ABIN1108021

This Mouse Monoclonal antibody specifically detects Laminin gamma 1 in IP, IHC (fro) and EIA. It exhibits reactivity toward Human.

Quick Overview for Laminin gamma 1 antibody (ABIN1108021)

Target: Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Laminin gamma 1 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: BC17

Product Details anti-Laminin gamma 1 Antibody

Specificity: The antibody recognizes the Mr 200,000 gamma-1-chain of Human reduced and Alkylated Laminin produced by various cultured cells, which produce Laminins complexed with it. The specificity of Mab BC17 has been confirmed by Immunoprecipitation and ELISA by using recombinant gamma-1- chain. The antibody only reacts with Human cells and tissues (further studies are going on).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ig Fraction

Immunogen: Pepsin-digested laminins from Human placenta. Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1.0 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for Laminin gamma 1

Target: Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Alternative Name: Laminin gamma 1

Background: Laminin, a major structural glycoprotein of the basement membranes, is an attachment and survival factor for epithelial cells and can also promote the growth of epithelial cells. Laminin plays an important role in both the structural organization of basement membranes and in the anchorage of cells. The monoclonal antibody, DG10 and BC17 against laminin chain ß1 and γ1, respectively can be widely applied in immunohistochemical studies as all basement membranes contain laminin trimers containing these chains. Antibodies to laminin chains are useful in basic biology studies as well as in pathological studies concerning, for instance, the integrity of the basement membranes in carcinomas.Synonyms: LAMB2, LAMC1, Laminin B2 chain, Laminin subunit gamma-1

Gene ID: 3915

NCBI Accession: NP_002284

UniProt: P11047