Myoferlin antibody

Catalog No. ABIN1108357

This Mouse Monoclonal antibody specifically detects Myoferlin in WB, EIA and IHC (fro). It exhibits reactivity toward Human and Mouse.

Quick Overview for Myoferlin antibody (ABIN1108357)

Target: Myoferlin (MYOF)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Myoferlin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 7D2

Product Details anti-Myoferlin Antibody

Specificity: This antibody reacts with Human 234 kDa FER1L3 protein. Cross reacts with Mouse protein.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography on Protein A

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Target Details for Myoferlin

Target: Myoferlin (MYOF)

Alternative Name: Myoferlin

Background: Myoferlin belongs to the ferlin family and contains five C2 domains. It is a calcium/phospholipid binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. It is also involved in endocytic recycling and implicated in VEGF signal transduction by regulating the levels of the receptor KDR. Myoferlin is expressed in myoblast and endothelial cells (at protein level), highly expressed in cardiac and skeletal muscles, also present in lung and at very low levels in kidney, placenta and brain. There are eight named isoforms.Synonyms: FER1L3, KIAA1207, MYOF

Gene ID: 26509