Myoglobin antibody (C-Term)
Quick Overview for Myoglobin antibody (C-Term) (ABIN1108359)
Target
See all Myoglobin (MB) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- Reacts with Mouse 17 kDa protein. May cross-react with Rat and Human due to sequence homology.
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Purification
- Purified
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Immunogen
- Synthetic peptide derived from C-terminal domain of Mouse Mb protein.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- Restore in distilled water.
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Buffer
- 0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Myoglobin (MB)
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Alternative Name
- Myoglobin
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Background
- Myoglobin (MB), with 154-amino acid protein (about 17 kDa), is a member of the globin superfamily and expression of myoglobin is highest in skeletal and cardiac muscle. Functionally, myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. Myoglobin is also thought to buffer intracellular O2 concentration when muscle activity increases and to facilitate intracellular O2 diffusion by providing a parallel path that augments simple diffusion of dissolved O2. Furthermore, myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.Synonyms: MB
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Gene ID
- 17189
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NCBI Accession
- NP_001157519
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Pathways
- Brown Fat Cell Differentiation
Target
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