Nebulin antibody

Catalog No. ABIN1108401

The Mouse Monoclonal anti-Nebulin antibody (Clone Neb-20) (ABIN1108401) specifically detects Nebulin in WB. The antibody is reactive with Human, Mouse, Rat, Chicken and Frog samples.

Quick Overview for Nebulin antibody (ABIN1108401)

Target: Nebulin (NEB)

Reactivity: Human, Mouse, Rat, Chicken, Frog

Host: Mouse

Clonality: Monoclonal

Conjugate: This Nebulin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: Neb-20

Product Details anti-Nebulin Antibody

Specificity: This antibody reacts to Nebulin.

Purification: Affinity chromatography

Immunogen: Chicken breast nebulin

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Nebulin

Target: Nebulin (NEB)

Alternative Name: Nebulin

Target Type: Chemical

Background: Nebulin is a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4 % of the total myofibrillar protein and its size varies from 600 to 800 kD in a manner that is tissue-, species-,and developmental stage-specific. The nebulin gene contains 183 exons in a 249-kb genomic region. Nebulin is mapped to chromosome 2. Nebulin is a giant filamentous protein specific for vertebrate skeletal muscles. Mutations in the nebulin gene associated with autosomal recessive nemaline myopathy.Synonyms: NEB

Gene ID: 4703

NCBI Accession: NP_004534

UniProt: P20929