PRTN3 antibody

Catalog No. ABIN1108718

The Mouse Monoclonal anti-PRTN3 antibody has been validated for WB and EIA. It is suitable to detect PRTN3 in samples from Human.

Quick Overview for PRTN3 antibody (ABIN1108718)

Target: PRTN3 (Proteinase 3 (PRTN3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRTN3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 3B4

Product Details anti-PRTN3 Antibody

Specificity: This antibody reacts to Proteinase 3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein G

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.03 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for PRTN3

Target: PRTN3 (Proteinase 3 (PRTN3))

Alternative Name: PR3 / C-ANCA

Background: Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.Synonyms: AGP7, Leukocyte proteinase 3, MBN, Myeloblastin, NP-4, Neutrophil proteinase 4, P29, PR-3, PRTN3, Proteinase 3, Wegener autoantigen

Molecular Weight: 28 kDa

Gene ID: 5657