The Rabbit Polyclonal anti-SUPT5H antibody (ABIN1109175) specifically detects SUPT5H in WB and IHC (p).
The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken and Xenopus laevis samples.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Reconstitution
Add 50 μL of distilled water to a final concentration of 1 mg/mL.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
SUPT5H and its binding partner regulate transcriptional elongation by RNA polymerase II. SPT4 and SPT5 are involved in both 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB)-mediated transcriptional inhibition and the activation of transcriptional elongation by the human immunodeficiency virus type 1 (HIV-1) Tat protein.Synonyms: DRB sensitivity-inducing factor large subunit, DSIF p160, DSIFp160, SPT5, SPT5H, Tat-CT1 protein, Tat-cotransactivator 1 protein, Transcription elongation factor SPT5