TGFB2 antibody (N-Term)

Catalog No. ABIN1109226

This anti-TGFB2 antibody is a Rabbit Polyclonal antibody detecting TGFB2 in WB, IHC (fro) and EIA. Suitable for Human.

Quick Overview for TGFB2 antibody (N-Term) (ABIN1109226)

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Product Details anti-TGFB2 Antibody

Binding Specificity: N-Term

Specificity: Reacts with Human 48 kDa TGFB2 protein.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography on Protein A

Immunogen: Synthetic peptide derived from N-terminal domain of Human TGFB2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in distilled water.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer

Target Details for TGFB2

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Alternative Name: TGF-beta-2 (TGFB2)

Background: Transforming growth factor beta's (TGF beta's) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFalpha. It is now realized that TGF beta's mediate many cell-cell interactions that occur during embryonic development. Three TGF beta's have been identified in mammals. TGFB1, TGFB2 and TGFB3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF beta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFB3 protein has approximately 80 % identity to the mature region of both TGFB1 and TGFB2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity.Synonyms: BSC-1 cell growth inhibitor, Cetermin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Polyergin, Transforming growth factor beta-2

Gene ID: 7042

NCBI Accession: NP_001129071

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus