TMPRSS3 antibody

Catalog No. ABIN1109275

This Rabbit Polyclonal antibody specifically detects TMPRSS3 in WB, EIA and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for TMPRSS3 antibody (ABIN1109275)

Target: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TMPRSS3 Antibody

Specificity: This antibody reacts with 49 kDa TMPRSS3 protein.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Antigen Affinity Chromatography

Immunogen: A 15 residue synthetic peptide derived from specific domain of Human TMPRSS3 protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 0.1 M Tris, 0.1 M Glycine, 50 % Glycerol ( pH 7.8), 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store antibody (in aliquots) at -20 °C.

Target Details for TMPRSS3

Target: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Alternative Name: TMPRSS3

Background: TMPRSS3 is a 437 amno acid membrane bound serine protease and a member of the S1 peptidase family. TMPRSS3 contains an amino-terminal signalanchor sequence and a glycosylated extracellular region containing the serine protease domain. Two novel missense mutations of TMPRSS3, W251C and P404L, alter the highly conserved amino acids of the serine protease domain. TMPRSS3 is expressed in many tissues, including fetal cochle,a a subset of pancreatic cancer and various other cancer tissues. TMPRSS3 is also overexpressed in cancer, suggesting that it may be important for processes in metastasis formation and tumor invasion.Synonyms: ECHOS1, TADG-12, TADG12, Transmembrane protease serine 3, Tumor-associated differentially-expressed gene 12 protein

Gene ID: 64699

NCBI Accession: NP_076927

Pathways: Sensory Perception of Sound