TRIM13 antibody (Middle Region)
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- Target See all TRIM13 Antibodies
- TRIM13 (Tripartite Motif Containing 13 (TRIM13))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRIM13 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Sequence
- DTLETSKRKS LQLLTKDSDK VKEFFEKLQH TLDQKKNEIL SDFETMKLAV
- Cross-Reactivity (Details)
- Species reactivity (expected):Rat, Mouse, BovineSpecies reactivity (tested):Human
- Purification
- Purified using peptide immunoaffinity column
- Immunogen
- The immunogen for anti-TRIIM13 antibody: synthetic peptide directed towards the middle region of human TRIM13
- Top Product
- Discover our top product TRIM13 Primary Antibody
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anti-Tripartite Motif Containing 13 (TRIM13) (Middle Region) antibody
TRIM13 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 40-310) antibodyTRIM13 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (Middle Region) antibodyTRIM13 Reactivity: Human, Mouse, Rat, Cow WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 1-100) antibodyTRIM13 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 165-214) antibodyTRIM13 Reactivity: Human, Rat, Cow, Guinea Pig, Horse, Rabbit, Bat, Hamster, Monkey, Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 40-310) antibodyTRIM13 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 61-90), (N-Term) antibodyTRIM13 Reactivity: Human WB Host: Rabbit Polyclonal RB33240 unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) antibodyTRIM13 Reactivity: Human IF Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 51-100) antibodyTRIM13 Reactivity: Human, Rat, Cow WB Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 13 (TRIM13) (AA 181-230) antibodyTRIM13 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Bat, Hamster, Monkey, Pig WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- Target
- TRIM13 (Tripartite Motif Containing 13 (TRIM13))
- Alternative Name
- TRIM13 / RNF77 (TRIM13 Products)
- Background
- TRIM13 is an E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. TRIM13 enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation, regulates ER stress-induced autophagy, and may act as a tumor suppressor.Synonyms: B-cell chronic lymphocytic leukemia tumor suppressor Leu5, LEU5, Leukemia-associated protein 5, Putative tumor suppressor RFP2, RFP2, RING finger protein 77, Tripartite motif-containing protein 13
- Gene ID
- 10206
- NCBI Accession
- NP_005789
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