14-3-3 eta antibody

Catalog No. ABIN1110129

This anti-14-3-3 eta antibody is a Mouse Monoclonal antibody detecting 14-3-3 eta in WB and IF. Suitable for Human, Mouse and Rat.

Quick Overview for 14-3-3 eta antibody (ABIN1110129)

Target: 14-3-3 eta (YWHAH)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This 14-3-3 eta antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-14-3-3 eta Antibody

Purification: purified

Immunogen: Purified, E. coli-derived, recombinant human 14-3-3 eta protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Target Details for 14-3-3 eta

Target: 14-3-3 eta (YWHAH)

Alternative Name: 14.3.3 (eta)

Background: The 14. 3. 3 family of proteins were originally discovered as prominent protein spots on 2 dimensional gels. They are a family of 28-33 kDa proteins which are often major proteins of the cytoplasm (1). They function as binding partners for phosphoserine and phosphthreonine sites in other proteins, though they have other binding partners which are not dependent on phosphorylation. These binding interactions are important in the regulation of molecules such as the signaling kinases in the MAP kinase pathway c-Raf and b-Raf, the proapoptotic molecules Bad and Bax and the cell cycle regulator Cdc25.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction