MBP antibody

Catalog No. ABIN1110155

The Mouse Monoclonal anti-MBP antibody has been validated for WB and IF. It is suitable to detect MBP in samples from Human and Rat.

Quick Overview for MBP antibody (ABIN1110155)

Target: MBP (Myelin Basic Protein (MBP))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This MBP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-MBP Antibody

Purification: Ascites

Immunogen: Mixture of 3 MBP peptides which are the different forms of the protein which are alternate transcription from a single gene.

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Target Details for MBP

Target: MBP (Myelin Basic Protein (MBP))

Alternative Name: Myelin Basic Protein

Background: Myelin basic protein is reported to account for about 30 of the proteins in myelin found in the central nervous system. It can induce experimental allergic encephalomyelitis (EAE), a T-lymphocyte mediated disease due to delayed-type hypersensitivity, though each animal species appears to respond to a different fragment of the 170 amino acid polypeptide. Four different isoforms have been identified through cDNA cloning. All four of these variants are identical except for the insertion or deletion of two peptide fragments encoded by exons 2 and 5. Myelin basic protein is reported to be expressed in oligodendrocytes, myelin of white matter in the brain and spinal cord and in peripheral nerves, though it is expressed less abundantly in gray matter. Image: