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POMC antibody (C-Term)

This Mouse Monoclonal antibody specifically detects POMC in IHC (p), IHC (fro) and EIA. It exhibits reactivity toward Human and Rat.
Catalog No. ABIN111034

Quick Overview for POMC antibody (C-Term) (ABIN111034)

Target

See all POMC Antibodies
POMC (Proopiomelanocortin (POMC))

Reactivity

  • 70
  • 42
  • 42
  • 2
  • 1
  • 1
Human, Rat

Host

  • 61
  • 36
  • 1
Mouse

Clonality

  • 60
  • 38
Monoclonal

Conjugate

  • 68
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This POMC antibody is un-conjugated

Application

  • 42
  • 39
  • 32
  • 29
  • 20
  • 18
  • 17
  • 13
  • 13
  • 13
  • 10
  • 8
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone

56
  • Binding Specificity

    • 16
    • 10
    • 9
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificity

    Reacts with Human and Rat C-terminal ACTH. Specific for CLIP (17-39 ACTH) and does not cross-react with Synacthen (1-24 ACTH).

    Purification

    Protein A Chromatography

    Immunogen

    ACTH-BSA Conjugate Remarks:

    Isotype

    IgG1
  • Application Notes

    Reacts with solid phase ACTH either captured as part of a sandwich or adsorbed as a solidphase antigen and as such is suitable for serum assay development. Also reactive onformalin-fixed paraffin wax embedded tissue and is therefore suitable forimmunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS containing 0.09 % Sodium Azide as preservative

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    POMC (Proopiomelanocortin (POMC))

    Alternative Name

    POMC

    Background

    ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.Synonyms: Adrenocorticotropic hormone, Corticotropin, POMC

    Gene ID

    5443

    NCBI Accession

    NP_000930

    UniProt

    P01189

    Pathways

    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
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