Lactate Dehydrogenase A antibody

Catalog No. ABIN1112818

This Mouse Monoclonal antibody specifically detects Lactate Dehydrogenase A in WB. It exhibits reactivity toward Mouse.

Quick Overview for Lactate Dehydrogenase A antibody (ABIN1112818)

Target: Lactate Dehydrogenase A (LDHA)

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lactate Dehydrogenase A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: L46-2

Product Details anti-Lactate Dehydrogenase A Antibody

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the N-terminal of human LDH-A.

Isotype: IgG1

Application Details

Application Notes: WB (1:500). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Lactate Dehydrogenase A

Target: Lactate Dehydrogenase A (LDHA)

Alternative Name: Lactate dehydrogenase A, LDH-A

Background: Lactate dehydrogenase A, also known as LDHA, is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. It is encoded by the LDHA gene which contains 7 exons and spans about 12 kb . It catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. Mutations in LDHA have been linked to exertional myoglobinuria.

Pathways: Warburg Effect