CD8 antibody
Quick Overview for CD8 antibody (ABIN1112856)
Target
See all CD8 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- affinity purified
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Isotype
- IgG
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Application Notes
- WB (1:500), ICC (1:50-200). Other applications have not been tested. The optimal dilutions should be determined by end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
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Preservative
- Sodium azide, Thimerosal (Merthiolate)
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
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Expiry Date
- 12 months
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- CD8
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Alternative Name
- CD8
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Background
- CD8 (cluster of differentiation 8, also known as T-cell antigen T8/LEU2) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. 1 The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides, but is frequently lost in other T-cell neoplasms. 2
Target
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