The Rabbit Polyclonal anti-Neisseria Gonorrhoeae antibody is suitable to detect Neisseria Gonorrhoeae in samples from Neisseria Gonorrhoeae. It has been validated for EIA.
Suitable for use in immunocytochemistry and ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
1-2 mg/mL (OD280 nm, E0.1% = 1.4)
Buffer
PBS containing 10 mg/mL BSA as stabilizer and 0.002 % Thimerosal as preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
Neisseria Gonorrhoeae
Target Type
Bacteria
Background
Neisseria gonorrhoeae infections are acquired by sexual contact and usually affect the mucous membranes of the urethra in males and the endocervix and urethra in females, although the infection may disseminate to a variety of tissues. The pathogenic mechanism involves the attachment of the bacterium to nonciliated epithelial cells via pili (fimbriae) and the production of lipopolysaccharide endotoxin. Similarly, the lipopolysaccharide of Neisseria meningitidis is highly toxic, as it has an additional virulence factor in the form of its antiphagocytic capsule. Both pathogens produce IgA proteases which promote virulence. Many normal individuals may harbor Neisseria meningitidis in the upper respiratory tract, but Neisseria gonorrhoeae is never part of the normal flora and is only found after sexual contact with an infected person (or direct contact, in the case of infections in the newborn).