Reactivity: Mycobacterium tuberculosis
IHC (p), IFA
Host: Rabbit
Polyclonal
Biotin
Application Notes
Suitable for immunohistochemistry and IFA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
1-2 mg/mL (OD280 nm, E0.1% = 1.4)
Buffer
PBS containing 10 mg/mL BSA as stabilizer and 0.002 % Thimerosal as preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.
Target
M. tuberculosis
(Mycobacterium Tuberculosis)
Target Type
Bacteria
Background
Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure, most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65.Synonyms: M. tuberculosis, TB