HBSAg antibody (Subtype ad/ay)

Catalog No. ABIN112971

Cited in 1 publication. The Rabbit Polyclonal anti-HBSAg antibody (ABIN112971) specifically detects HBSAg in EIA. The antibody is reactive with Hepatitis B Virus (HBV) samples.

Quick Overview for HBSAg antibody (Subtype ad/ay) (ABIN112971)

Target: HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))

Reactivity: Hepatitis B Virus (HBV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBSAg antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-HBSAg Antibody

Binding Specificity: Subtype ad/ay

Virus Strain: Subtype ad/ay

Purification: Protein A affinity chromatography

Purity: > 95 % pure

Immunogen: Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay.

Application Details

Application Notes: Suitable for use in ELISA. Also suitable for conjugation purposes.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 4-5 mg/mL (OD280 nm, E0.1% = 1.4)

Buffer: 0.01 M PBS, pH 7.2, with 0.09 % sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-HBSAg antibody (ABIN112971)

Lünsdorf, Gurramkonda, Adnan, Khanna, Rinas: "Virus-like particle production with yeast: ultrastructural and immunocytochemical insights into Pichia pastoris producing high levels of the hepatitis B surface antigen." in: Microbial cell factories, Vol. 10, pp. 48, (2011) (PubMed).

Target Details for HBSAg

Target: HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))

Alternative Name: Hepatitis B Surface Antigen / HBsAg

Target Type: Viral Protein

Background: Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.Synonyms: HBV surface antigen, Hepatitis B Virus