Western blot (1/250-1/500). Immunoprecipitation (1/25-1/100). Immuno-histochemistry on frozen sections (1/100). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Preservative
Azide free
Handling Advice
Avoid repeated freeze-thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
SCG2
(Secretogranin II (SCG2))
Alternative Name
Secretogranin-2 (SCG2)
Background
Chromogranin C belongs to the family of neuroendocrine secretory proteins. Studies in rodents suggest that the full length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.Synonyms: CHGC, Chromogranin-C, Secretogranin II, Sg-II, SgII