PACAP antibody

Catalog No. ABIN113928

The Sheep Polyclonal anti-PACAP antibody (ABIN113928) specifically detects PACAP in EIA and RIA. The antibody is reactive with Human samples.

Quick Overview for PACAP antibody (ABIN113928)

Target: PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This PACAP antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

Product Details anti-PACAP Antibody

Specificity: This antibody recognizes PACAP-38 and has the follwing cross recativities (All tested in simple ELISA assay): PACAP-38: 100 % PACAP Immunogen: 75 % PACAP-27: 22 % PACAP Related Peptide: 9 % VIP: 2 %.

Purification: Affinity Chrpomatography on Protein G

Immunogen: Proprietory, 14 amino acid peptide sequence of PACAP-38, conjugated to KLH.

Isotype: IgG

Application Details

Application Notes: ELISA. Radioimmunoassay (1/60).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 5.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PACAP

Target: PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))

Alternative Name: ADCYAP1 / PACAP

Background: PACAP receptor (pituitary adenylate cyclase activating polypeptide type 1 receptor) is a receptor for PACAP 27 and PACAP 38. It is a G protein coupled receptor (GPCR) that may regulate the release of adrenocorticotropin, luteinising hormone, growth hormone, prolactin, epinephrine, and catecholamine. PACAP receptor may play a role in spermatogenesis and sperm motility and also causes smooth muscle relaxation and secretion in the gastrointestinal tract.Synonyms: Pituitary adenylate cyclase-activating polypeptide

Gene ID: 116

NCBI Accession: NP_001093203

UniProt: P18509

Pathways: Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Activity, cAMP Metabolic Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Regulation of G-Protein Coupled Receptor Protein Signaling