CD3 antibody

Catalog No. ABIN115288

This Rabbit Polyclonal antibody specifically detects CD3 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD3 antibody (ABIN115288)

Target: CD3

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CD3 Antibody

Specificity: This antibody reacts with intracytoplasmic portion of the CD3 antigen on the T cells.
Cellular Localization: Cell membrane

Purification: Purified

Immunogen: Synthetic human CD3 polypeptide conjugated to bovine serum albumin.

Application Details

Application Notes: Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 10-1: 50 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Tonsil
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: containing 0.5 % BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD3

Target: CD3

Alternative Name: CD3

Background: It stains T cells in cortex as well as medulla of the thymus and lymphoid tissues. This antibody also labels T cell neoplasm, malignant histiocytes and in Hodgkin's disease.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4

Gene ID: 916

NCBI Accession: NP_000724

UniProt: P07766

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway