F13A1 antibody

Catalog No. ABIN115411

This Rabbit Polyclonal antibody specifically detects F13A1 in IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for F13A1 antibody (ABIN115411)

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F13A1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-F13A1 Antibody

Specificity: This antibody reacts with a 160 kDa (unreacted dimer) and 80 kDa (reduced monomer) protein.
Cellular Localization: Cytoplasmic, nuclear.

Purification: Purified

Immunogen: Recombinant protein corresponding to A-subunit of coagulation Factor XIII a Genename: F13A1

Application Details

Application Notes: Immunohistochemistry on Frozen and Paraffin sections.1/25-1/50 dilution in an ABCmethod. We suggest an incubation period of 30 minutes at room temperature. Formalinfixed paraffin embedded tissue sections require high temperature antigen unmasking with10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Placenta.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month. DO NOT FREEZE!

Target Details for F13A1

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Alternative Name: Coagulation Factor XIIIa (F13A1)

Background: Factor XIII is a beta-globulin found in plasma and is composed of two subunits. Factor XIII-A is the catalytic subunit and is a dimmer of M.W. 160 kD. Factor XIII is a dermal dendrocyte marker and shows variable reaction with these types of tumors. Factor XIII can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system.Synonyms: Coagulation factor XIII A chain, F13A, Protein-glutamine gamma-glutamyltransferase A chain, Transglutaminase A chain

Gene ID: 2162

NCBI Accession: NP_000120

UniProt: P00488