MYL3/CMLC1 antibody

Catalog No. ABIN115509

This anti-MYL3/CMLC1 antibody is a Rabbit Polyclonal antibody detecting MYL3/CMLC1 in WB and EIA. Suitable for Human.

Quick Overview for MYL3/CMLC1 antibody (ABIN115509)

Target: MYL3/CMLC1 (MYL3) (Myosin, Light Chain 3 (MYL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYL3/CMLC1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-MYL3/CMLC1 Antibody

Specificity: This antibody reacts to ventricular myosin light chain.

Purification: Immunoaffinity chromatography

Immunogen: Recombinant human myosin (cardiac) light chain fragment. Remarks: The antibody was raised in rabbits by immunization with the recombinant Human Myosin (Cardiac) Light Chain fragment. The amino acid sequence of the recombinant Human Myosin (Cardiac) Light Chain fragment is 100% homologous to the amino acid sequence of the human serum Myosin (Cardiac) Light Chain fragment.

Application Details

Application Notes: ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 0.05 mL of deionized water

Concentration: 1.0 mg/mL

Buffer: 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE

Preservative: Azide free

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 months.

Expiry Date: 6 months

Target Details for MYL3/CMLC1

Target: MYL3/CMLC1 (MYL3) (Myosin, Light Chain 3 (MYL3))

Alternative Name: MYL3

Background: Human ventricular myosin light chain (MLC-I, Essential Myosin Light Chain Isoform) is a 21 kDa cardiac contractile protein, which is one of component of myosin structure. The protein MLC-I is present in the contractile apparatus and not in cytosol. In severe congestive heart failure (CHF), myofibrils may degenerate and, subsequently, the myofibrillar components may be released into the circulation. The increased blood levels of MLC-I could indicate morphological changes in CHF, myocardial infarction, structural abnormalities in viable myocytes also observed in non-ischaemic CHF, myocardial necrosis.Synonyms: CMLC1, Cardiac myosin light chain 1, MLC1SB, Myosin light chain 1, Myosin light chain 3, Ventricular/slow twitch myosin alkali light chain, slow-twitch muscle B/ventricular isoform

Gene ID: 4634

NCBI Accession: NP_000249

UniProt: P08590