BMP2 antibody (C-Term)

Catalog No. ABIN115692

This anti-BMP2 antibody is a Rabbit Polyclonal antibody detecting BMP2 in WB, IP and EIA. Suitable for Human.

Quick Overview for BMP2 antibody (C-Term) (ABIN115692)

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Product Details anti-BMP2 Antibody

Binding Specificity: C-Term

Sequence: C(SH)-L-D-E-Y-D-K-V-V-L-K-N-Y-Q-E-M-V-V-E-G.

Specificity: This polyclonal serum antibody DP3515 will detect Human BMP-2/4.

Cross-Reactivity (Details): Also reacts to: BMP4

Purification: Protein A Chromatography.

Immunogen: Highly purified Synthetic peptide C-terminal (20 amino acids) of Human BMP-2/4.

Application Details

Application Notes: ELISA: 1.0 μg/mL). Western Blot: 1 μg/mL, it will detect 20 ng/lane of recombinant human BMP-2/4-1 orBMP-2/4-2 under reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: After reconstitition add preservatives (0.02 % Sodium Azide or 0.03 % Thimerosal).

Buffer: PBS without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Alternative Name: BMP2 / BMP2A

Background: BMP2 belongs to the transforming growth factor beta (TGFB) superfamily of secreted growth factors. It is a disulfide linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.Synonyms: BMP-2, BMP-2A, Bone morphogenetic protein 2

Gene ID: 650

NCBI Accession: NP_001191

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation