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IL-20 antibody

This Goat Polyclonal antibody specifically detects IL-20 in WB and EIA. It exhibits reactivity toward Human.
Catalog No. ABIN116425

Quick Overview for IL-20 antibody (ABIN116425)

Target

See all IL-20 (IL20) Antibodies
IL-20 (IL20) (Interleukin 20 (IL20))

Reactivity

  • 36
  • 18
  • 8
  • 2
Human

Host

  • 40
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  • 1
Goat

Clonality

  • 45
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Polyclonal

Conjugate

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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This IL-20 antibody is un-conjugated

Application

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Purification

    Affinity chromatography.

    Immunogen

    Highly pure (>98%) recombinant hIL-20
  • Application Notes

    Neutralization. ELISA: To detect hIL-20 by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hIL-20. Western Blot: To detect hIL-20 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIL-20 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Reconstitution

    Restore in sterile water to a concentration of > 0.2 mg/mL.

    Buffer

    PBS, pH 7.2 without preservatives.

    Preservative

    Without preservative

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Target

    IL-20 (IL20) (Interleukin 20 (IL20))

    Alternative Name

    Interleukin-20 / IL20

    Background

    IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.Synonyms: IL-20, ZCYTO10

    Gene ID

    50604

    NCBI Accession

    NP_061194

    UniProt

    Q9NYY1

    Pathways

    Protein targeting to Nucleus
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