CCL3L1 antibody

Catalog No. ABIN116429

The Goat Polyclonal anti-CCL3L1 antibody has been validated for WB and EIA. It is suitable to detect CCL3L1 in samples from Human.

Quick Overview for CCL3L1 antibody (ABIN116429)

Target: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CCL3L1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CCL3L1 Antibody

Purification: Affinity chromatography employing immobilized hLD78-Beta matrix.

Immunogen: Highly pure (>98%) recombinant hLC78-beta

Application Details

Application Notes: Neutralization. ELISA: To detect hLD78-Beta by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hLD78-Beta. Western Blot: To detect hLD78-Beta by Western Blot analysis this antibody can be used ata concentration of 0.1- 0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hLD78-Beta is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration of > 0.2 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Target Details for CCL3L1

Target: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Alternative Name: LD78 beta / CCL3L1

Background: LD78 belongs to the intercrine beta (chemokine CC) family. It is closely related to MIP-1 alpha. This protein binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, binding of this protein to CCR5 inhibits HIV entry, and LD78 beta has been shown to exhibit potent activity in HIV suppression assays. The copy number of the LD78 gene varies among individuals, most individuals have 1-6 copies in the diploid genome, although rare individuals have zero or more than six copies. The gene encodes a 93 amino acid preprotein, the mature protein contains 70 amino acids.Synonyms: C-C motif chemokine 3-like 1, D17S1718, G0/G1 switch regulatory protein 19-2, G0S19-2, SCYA3L1, Small-inducible cytokine A3-like 1, Tonsillar lymphocyte LD78 beta protein

Gene ID: 414062

NCBI Accession: NP_001001437

UniProt: P16619

Pathways: Cellular Response to Molecule of Bacterial Origin