DLK1 antibody (Extracellular Domain)

Catalog No. ABIN1169189

The Rabbit Polyclonal anti-DLK1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect DLK1 in samples from Human.

Quick Overview for DLK1 antibody (Extracellular Domain) (ABIN1169189)

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DLK1 Antibody

Binding Specificity: Extracellular Domain

Specificity: Recognizes human DLK1. Detects a band of ~42 kDa by Western blot.

Cross-Reactivity: Human

Cross-Reactivity (Details): Weakly cross-reacts with mouse Dlk1.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human DLK1 (extracellular domain).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Expiry Date: 6 months

Target Details for DLK1

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Alternative Name: DLK1

Background: The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

UniProt: P80370