CD42a antibody

Catalog No. ABIN118642

This Mouse Monoclonal antibody specifically detects CD42a in FACS and IP. It exhibits reactivity toward Human.

Quick Overview for CD42a antibody (ABIN118642)

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD42a antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: GRP-P

Product Details anti-CD42a Antibody

Specificity: This antibody recognises the platelet GP1X antigen.

Purification: Ion exchange chromatography

Immunogen: Human red blood cells and platelets. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Flow cytometry. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD42a

Target: CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))

Alternative Name: CD42a / GPIX

Background: CD42a is a small membrane glycoprotein found on the surface of human platelets. It forms a one to one noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain and a beta chain, that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with GP9 and platelet glycoprotein V. CD42a is present on thrombocytes and also on a so far unidentified subpopulation of T lymphocytes.Synonyms: GP-IX, GP9, Glycoprotein 9, Platelet glycoprotein IX

Gene ID: 2815

NCBI Accession: NP_000165

UniProt: P14770