ITGA2 antibody (FITC)
Quick Overview for ITGA2 antibody (FITC) (ABIN118698)
Target
See all ITGA2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody recognizes the Integrin alpha 2 subunit (CD49b/ITGA2).
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Purification
- Affinity Chromatography on Protein G.
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Immunogen
- Spleen cells from immunised mice were fused with cells of the mouse NSI myeloma cell line.
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Isotype
- IgG1
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Application Notes
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Flow Cytometry (Neat - 1/5): Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing. Dilute only prior to immediate use
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ITGA2 (Integrin alpha 2 (ITGA2))
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Alternative Name
- CD49b / ITGA2
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Background
- CD49b is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit (CD29) to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, endothelial cells, monocytes and most adherent cell lines.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2
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Gene ID
- 3673
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NCBI Accession
- NP_002194
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UniProt
- P17301
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Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
Target
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