CD86 antibody (FITC)

Catalog No. ABIN118805

The Mouse Monoclonal anti-CD86 antibody has been validated for FACS. It is suitable to detect CD86 in samples from Human.

Quick Overview for CD86 antibody (FITC) (ABIN118805)

Target: CD86

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD86 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: BU63

Product Details anti-CD86 Antibody (FITC)

Specificity: This antibody recognises the CD86 antigen.

Purification: Affinity chromatography on Protein A

Immunogen: Human peripheral blood lymphocytes. Spleen cells from immunised mice were fused with cells of the mouse P3.X63 Ag8653 myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD86

Target: CD86

Alternative Name: CD86

Background: CD86 is a cell surface protein expressed by activated B cells and monocytes. CD86 is also known as B7-2, and is the second ligand for CD28 and CTLA-4, and may have an important role in co-stimulation of T cells in the primary immune response.Synonyms: Activation B7-2 antigen, B7.2, B70, BU63, CD28LG2, CTLA-4 counter-receptor B7.2, FUN-1, T-lymphocyte activation antigen CD86

Gene ID: 942

NCBI Accession: NP_008820

UniProt: P42081

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation