TNFSF9 antibody

Catalog No. ABIN119819

Product Details anti-TNFSF9 Antibody

Target: TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TNFSF9 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: This antibody recognises 4-1BB Ligand (CD137L).

Purification: Affinity Chromatography on Protein G

Immunogen: 41BBL-Fc Fusion Protein.

Clone: AT113-2

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry (1/10-1/50): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TNFSF9

Target: TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))

Alternative Name: 4-1BBL / TNFSF9 (TNFSF9 Products)

Background: CD137L is a 50kD type 2 transmembrane protein, which is a member of the TNF superfamily. In mice CD137L is expressed on activated T-cells, B-cells, macrophages and dendritic cells. Interaction of CD137L with its receptor 4-1BB (CD137) is reported to be involved in T and B cell growth and T cell effector function.Synonyms: 4-1BB ligand, CD137L, Tumor necrosis factor ligand superfamily member 9

Gene ID: 21950

NCBI Accession: NP_033430

UniProt: P41274

Pathways: Activated T Cell Proliferation, Cancer Immune Checkpoints