KIR2D antibody (PE)
Quick Overview for KIR2D antibody (PE) (ABIN119852)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody recognizes KIR2D members of the killer cell immunoglobulin (Ig)-like receptor (KIR) family, CD158a, CD158b and P50.3. Clone NKVFS1 specifically recognizes the long and short forms CD158a and CD158b (KIR2DL, KIR2DS1 and KIR2DS2 respectively) and also p50.3 (KIR2DS4). The clone is reported to have functional activity, activating NK cell cytotoxicity via KIR2DS and inhibiting via KIR2DL forms. We recommend the use of SM2036A for this purpose.
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Purification
- Affinity Chromatography on Protein G
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Isotype
- IgG1
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anti-KIR2D (KIR2D) (AA 44-202) antibody
KIR2D Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2H6 unconjugated
anti-KIR2D (KIR2D) antibodyKIR2D Reactivity: Human FACS, WB, EIA, IP, DNA Mic Host: Mouse Monoclonal NKVFS1 unconjugated
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Application Notes
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Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- SM2036R: Restore with 1 mL distilled water. SM2036RT: Restore with 0.25 mL distilled water.
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide, 5 % Sucrose and 1 % BSA
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing. Dilute only prior to immediate use.
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Storage
- -20 °C
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Storage Comment
- Aliquot contents and freeze at -20 °C or below.
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- KIR2D
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Alternative Name
- CD158 / KIR2D
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Background
- KIR2D family members are cell surface glycoproteins with two Ig domains, which are expressed on natural killer cells and some T cells.Synonyms: CD158a, CD158b, CD158i, KI2DL1, KILLER CELL Immunoglobin-Like Receptors, KIR2DL3, KIR2DS4
Target
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