hCG antibody (Domain Holo C3)

Catalog No. ABIN120020

The Mouse Monoclonal anti-hCG antibody has been validated for RIA and EIA. It is suitable to detect hCG in samples from Human.

Quick Overview for hCG antibody (Domain Holo C3) (ABIN120020)

Target: hCG (Chorionic Gonadotropin (hCG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This hCG antibody is un-conjugated

Application: Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)

Clone: INN-hCG-45

Product Details anti-hCG Antibody

Binding Specificity: Domain Holo C3

Specificity: This antibody reacts with holo-hCG recognising the c3 epitope on hCG. No subunit detection is observed. Can be used in combination with INN-hCG-22 and 24. Suitable for use as a capture antibody.

Purification: Ion exchange on Protein A

Immunogen: Human CG.

Isotype: IgG1

Application Details

Application Notes: ELISA. Radioimmunoassays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS pH 7.4 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for hCG

Target: hCG (Chorionic Gonadotropin (hCG))

Target Type: Hormone

Background: Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.Synonyms: CGB, CGB3, Choriogonadotropin subunit beta, beta hCG, hCG-beta

Gene ID: 1082

NCBI Accession: NP_000728

UniProt: P01233