CD55 antibody

Catalog No. ABIN120605

The Mouse Monoclonal anti-CD55 antibody is suitable to detect CD55 in samples from Human and Primate. It has been validated for FACS, IP and IHC (p).

Quick Overview for CD55 antibody (ABIN120605)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD55 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MEM-118

Product Details anti-CD55 Antibody

Cross-Reactivity (Details): Species reactivity (tested):Human, non-Human Primates

Purification: Precipitation Methods and Size-Exclusion Chromatography

Immunogen: HPB-ALL human T cell line

Isotype: IgM

Application Details

Application Notes: Flow Cytometry. Immunoprecipitation. Immunohistochemistry (paraffin sections) Recommended dilution: 10 m g/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4 with 15 mM Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody at 2 - 8 °C. Do not freeze.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name: CD55 / DAF

Background: CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.Synonyms: Complement decay-accelerating factor

UniProt: P08174

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity