CD9 antibody
Quick Overview for CD9 antibody (ABIN120622)
Target
See all CD9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Clone IVA50 reacts with CD9 antigen, a 24 kDa single transmembrane polypeptide expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
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Purification
- Protein A affinity chromatography
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Purity
- > 95 % by SDS-PAGE
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Immunogen
- Bovine thrombocytes
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Isotype
- IgG2
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Application Notes
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Flow cytometry. Immunoprecipitation. Western blotting. Functional application (the antibody activates bovine thrombocytes).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, with 15 mM sodium azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
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Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
Expiry Date
- 12 months
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- CD9
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Alternative Name
- CD9
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Background
- CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.Synonyms: 5H9 antigen, Cell growth-inhibiting gene 2 protein, GIG2, Leukocyte antigen MIC3, MIC3, Motility-related protein, TSPAN29, Tetraspanin-29, p24
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Gene ID
- 280746
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UniProt
- P30932
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Pathways
- Response to Water Deprivation, Cell-Cell Junction Organization
Target
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