TNFSF4 antibody

Catalog No. ABIN120801

Product Details anti-TNFSF4 Antibody

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFSF4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody recognises OX40 (CD134) ligand (known as CD252). Clone OX89 has been reported to inhibit OX40/OX40L interaction. (1) SM326A is recomended for this purpose.

Purification: Affinity Chromatography on Protein G.

Immunogen: Rat CD4 and mouse CD134 ligand Chimaeric protein. Spleen cells from immunised PVG rats were fused with cells of the NS1 myeloma cell line

Clone: OX-89

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for TNFSF4

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Alternative Name: CD252 / TNFSF4 (TNFSF4 Products)

Background: CD252 expression has been shown to be restricted to activated dendritic cells, B cells and vascular endothelium.Synonyms: Glycoprotein Gp34, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, TXGP1, Tumor necrosis factor ligand superfamily member 4

Gene ID: 22164

UniProt: P43488

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints