MCHR2 antibody

Catalog No. ABIN122241

This anti-MCHR2 antibody is a Rabbit Polyclonal antibody detecting MCHR2 in IF and IHC (p). Suitable for Human.

Quick Overview for MCHR2 antibody (ABIN122241)

Target: MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCHR2 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MCHR2 Antibody

Specificity: Reacts with MCH Receptor type II (Family: GPCR, Subfamily: Melanin-concentrating hormone receptor)

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunocytochemistry. Immunohistochemistry with formalin fixed paraffin embedded tissues: 21 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for MCHR2

Target: MCHR2 (Melanin-Concentrating Hormone Receptor 2 (MCHR2))

Alternative Name: MCHR2 / GPR145

Background: MCHR2/GPR145 is a Melanin-Concentrating Hormone Receptor. Melanin-concentrating hormone plays an important role in the control of feeding behaviors and energy metabolism. Unlike MCH1, MCH2 signaling is not sensitive to pertussis toxin, and MCH2 cannot reduce forskolin-stimulated cAMP production. MCHR2/GPR145 is expressed predominantly in the brain. One EST has been isolated from a brain library.Synonyms: G-protein coupled receptor 145, GPRv17, MCH receptor 2, MCH-2R, MCH-R2, MCHR-2, Melanin-concentrating hormone receptor 2, SLT

Gene ID: 84539

UniProt: Q969V1