Cytokeratin 18 antibody
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- Target See all Cytokeratin 18 (KRT18) Antibodies
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Reactivity
- Human, Cow
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Cytokeratin 18 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- Specificity
- Ks 18.27 represents an excellent marker to discriminate simple epithelia from those of different origin. Polypeptide reacting: Mr 45,000 polypeptide (keratin K18, formerly also designated cytokeratin 18) of all simple type and complex epithelia. Reacts with human, bovine, negative with mouse. Reacts with MCF-7, HeLa. A-431, PLC, RT 112. All adeno-CA tested, undifferentiated CA, cervix CA, hepatocellular CA.
- Purification
- Protein A affinity chromatography
- Immunogen
- Cytoskeletal preparation from tumor cell line MCF-7.
- Clone
- Ks18-27
- Isotype
- IgG1
- Top Product
- Discover our top product KRT18 Primary Antibody
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anti-Keratin 18 (KRT18) antibody
KRT18 Reactivity: Human WB, FACS, ELISA, IHC (p), IP, ICC Host: Mouse Monoclonal DC-10 unconjugated
anti-Keratin 18 (KRT18) antibodyKRT18 Reactivity: Mammalian WB, FACS, ELISA, IHC (p), IP, ICC Host: Mouse Monoclonal C-04 unconjugated
anti-Keratin 18 (KRT18) (AA 53-150) antibodyKRT18 Reactivity: Human, Mouse, Rat, Pig WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 238-396) antibodyKRT18 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 1-423) antibodyKRT18 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 238-396) antibodyKRT18 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C2 unconjugated
anti-Keratin 18 (KRT18) (AA 102-396) antibodyKRT18 Reactivity: Human WB, IHC, IF, ELISA Host: Rabbit Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 72-380) antibodyKRT18 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 401-430), (C-Term) antibodyKRT18 Reactivity: Human, Mouse WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB18746 unconjugated
anti-Keratin 18 (KRT18) (AA 1-150) antibodyKRT18 Reactivity: Human WB, IHC, FACS, ELISA, ICC Host: Mouse Monoclonal 6G12F2 unconjugated
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- Application Notes
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Immunohistochemistry on frozen sections: 1: 10, 1 h at RT. Cytological material. Immunoblotting. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore in 1 mL dist. water
- Buffer
- PBS buffer, pH 7.4 containing 0.09 % sodium azide, 0.5 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- This product is photosensitive and should be protected from light
- Storage
- 4 °C
- Storage Comment
- Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- Target
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Alternative Name
- Cytokeratin 18 (KRT18 Products)
- Background
- Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
- Gene ID
- 3875
- NCBI Accession
- NP_000215
- UniProt
- P05783
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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