SERPINH1 antibody

Catalog No. ABIN127161

This anti-SERPINH1 antibody is a Rabbit Polyclonal antibody detecting SERPINH1 in WB, IHC (p) and IP. Suitable for Human, Mouse, Rat and Chicken.

Quick Overview for SERPINH1 antibody (ABIN127161)

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Reactivity: Human, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Product Details anti-SERPINH1 Antibody

Specificity: The antibody recognizes 47 kDa Hsp47.

Purification: Protein A Chromatography.

Immunogen: Synthetic peptide surrounding amino acid 407 of human HSP47

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS containing 30 % Glycerol, 0.5 % BSA, and 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C to -70 °C.

Target Details for SERPINH1

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Alternative Name: SERPINH1 / HSP47

Background: Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. HSP47 is a molecule expressed constitutively in cells that synthesizes collagen. HSP47 is a procollagen-specific molecular chaperon that resides in the endoplasmic reticulum of procollagen-producing cells and is essential for secretion of procollagen from cells. Significantly, HSP47 plays a vital role in folding and assembling collagen. HSP47 is also known as colligin 1, serpinh1, collagen binding protein 1 (CBP1) and gp46. The human HSP 47 gene encodes a 47 kDa protein.Synonyms: 47 kDa heat shock protein, Arsenic-transactivated protein 3, AsTP3, CBP1, CBP2, Cell proliferation-inducing gene 14 protein, Collagen-binding protein, Colligin, PIG14, Rheumatoid arthritis-related antigen RA-A47, SERPINH2, Serpin H1

Gene ID: 871

NCBI Accession: NP_001193943

UniProt: P50454