Cathepsin K antibody

Catalog No. ABIN127215

The Rabbit Polyclonal anti-Cathepsin K antibody (ABIN127215) specifically detects Cathepsin K in WB. The antibody is reactive with Human, Rat, Mouse, Pig, Rabbit and Chicken samples.

Quick Overview for Cathepsin K antibody (ABIN127215)

Target: Cathepsin K (CTSK)

Reactivity: Human, Rat, Mouse, Pig, Rabbit, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin K antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cathepsin K Antibody

Specificity: The antibody detects proform (43 kDa) and the mature form (29 kDa) of Cathepsin K.

Purification: Affinity Chromatography on Protein A.

Immunogen: Synthetic peptide surrounding amino acid 321 of Rat Cathepsin K

Application Details

Application Notes: Western blot (0.5-4 μg/mL). Has been reported by customer to work in Immunoprecipitation andImmunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA, and 0.01 % Thimerosal.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20 °C.

Target Details for Cathepsin K

Target: Cathepsin K (CTSK)

Alternative Name: Cathepsin K

Background: Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B, H, K, L, O, and S. The aspartyl protease class contains cathepsin D and E. Cathepsin G belongs to the serine protease class. Cathepsins are involved in various cellular events such as peptide biosynthesis, protein degradation, and apoptosis. Cathepsin K expression is highest in bone, cartilage, and skeletal muscle.Synonyms: CTSK, CTSO, CTSO2, Cathepsin O, Cathepsin O2, Cathepsin X

Gene ID: 1513

NCBI Accession: NP_000387

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades