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SDC4 antibody

This anti-SDC4 antibody is a Rabbit Polyclonal antibody detecting SDC4 in WB, IP, IHC (p) and IHC (fro). Suitable for Human, Mouse, Rat and Chicken.
Catalog No. ABIN127275

Quick Overview for SDC4 antibody (ABIN127275)

Target

See all SDC4 Antibodies
SDC4 (Syndecan 4 (SDC4))

Reactivity

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Human, Mouse, Rat, Chicken

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This SDC4 antibody is un-conjugated

Application

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Specificity

    This antibody detects Syndecan-4.

    Purification

    Protein A purified

    Immunogen

    Synthetic peptide surrounding amino acid 184 of human Syndecan-4
  • Application Notes

    Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 5-10 μg/mL. Immunohistochemistry (Frozen and paraffin sections): 15-25 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA, 0.01 % Thimerosal.

    Preservative

    Thimerosal (Merthiolate)

    Precaution of Use

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    -20 °C/-80 °C

    Storage Comment

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • Target

    SDC4 (Syndecan 4 (SDC4))

    Alternative Name

    Syndecan-4 (SDC4)

    Background

    Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is an matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.Synonyms: Amphiglycan, Ryudocan core protein, SYND4

    Gene ID

    6385

    NCBI Accession

    NP_002990

    UniProt

    P31431

    Pathways

    Glycosaminoglycan Metabolic Process
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