SDC4
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB36964
unconjugated
Application Notes
Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 5-10 μg/mL. Immunohistochemistry (Frozen and paraffin sections): 15-25 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C/-80 °C
Storage Comment
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
Target
SDC4
(Syndecan 4 (SDC4))
Alternative Name
Syndecan-4 (SDC4)
Background
Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is an matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.Synonyms: Amphiglycan, Ryudocan core protein, SYND4