SDC4 antibody

Catalog No. ABIN127275

The Rabbit Polyclonal anti-SDC4 antibody (ABIN127275) specifically detects SDC4 in WB, IP, IHC (p) and IHC (fro). The antibody is reactive with Human, Mouse, Rat and Chicken samples.

Quick Overview for SDC4 antibody (ABIN127275)

Target: SDC4 (Syndecan 4 (SDC4))

Reactivity: Human, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SDC4 Antibody

Specificity: This antibody detects Syndecan-4.

Purification: Protein A purified

Immunogen: Synthetic peptide surrounding amino acid 184 of human Syndecan-4

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 5-10 μg/mL. Immunohistochemistry (Frozen and paraffin sections): 15-25 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA, 0.01 % Thimerosal.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for SDC4

Target: SDC4 (Syndecan 4 (SDC4))

Alternative Name: Syndecan-4 (SDC4)

Background: Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is an matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.Synonyms: Amphiglycan, Ryudocan core protein, SYND4

Gene ID: 6385

NCBI Accession: NP_002990

UniProt: P31431

Pathways: Glycosaminoglycan Metabolic Process