FGF14 antibody (AA 1-252)

Catalog No. ABIN1304636

The Mouse Monoclonal anti-FGF14 antibody has been validated for WB, IHC, ICC and IP. It is suitable to detect FGF14 in samples from Mouse.

Quick Overview for FGF14 antibody (AA 1-252) (ABIN1304636)

Target: FGF14 (Fibroblast Growth Factor 14 (FGF14))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGF14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: N56-21

Product Details anti-FGF14 Antibody

Binding Specificity: AA 1-252

Specificity: Recognizes FGF14a and FGF14b No off-targets reported for FGF11, FGF12 or FGF13

Cross-Reactivity: Human, Mouse, Non-Human Primate, Rat

Characteristics:

Description: Our Anti-FGF14/FHF4 mouse monoclonal primary antibody is produced in-house from hybridoma clone N56/21. It is KO validated, detects mouse and rat FGF14/FHF4, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our FGF14/FHF4 mouse monoclonal primary antibody from hybridoma clone N56/21. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Purity: > 90% specific antibody

Immunogen: Fusion protein amino acids 1-252 (full-length) of mouse FGF14b (accession number O89096) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes:

Dilution Range: IP: 2 μg

Dilution Range: IHC: 1:500

Dilution Range: ICC: 1:500

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 24 months

Target Details for FGF14

Target: FGF14 (Fibroblast Growth Factor 14 (FGF14))

Alternative Name: FHF4

Background:

Synonyms: Fibroblast growth factor (FGF)

Target Description: Fibroblast growth factor 14, FHF4 or FGF14 is encoded by FGF14. FHF4 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF14 in found in both the hippocampus and the cerebellum localizes to the axon initial segment. Diseases associated with FGF14 include Spinocerebellar Ataxia and Autosomal Dominant Cerebellar Ataxia.

Gene Name Alternatives: Fgf14

Molecular Weight: 28 kDa

UniProt: O89096