GSG2 antibody (AA 1-798)
Quick Overview for GSG2 antibody (AA 1-798) (ABIN1304694)
Target
See all GSG2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-798
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Specificity
- No off-targets reported
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Cross-Reactivity
- Human
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Characteristics
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Description: Our Anti-Haspin/GSG2 mouse monoclonal primary antibody is produced in-house from hybridoma clone N128A/2. It detects human Haspin/GSG2, and is purified by Protein A chromatography. It is great for use in ICC, IP, WB.
Manufacturer Comment: We produce our Haspin/GSG2 mouse monoclonal primary antibody from hybridoma clone N128A/2. It is great in ICC, IP, WB and is purified by Protein A chromatography.
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Purification
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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Purity
- > 90% specific antibody
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Immunogen
- Fusion protein amino acids 1-798 (full-length) of human Haspin (accession number Q8TF76)
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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Storage
- 4 °C,-20 °C
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Storage Comment
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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Expiry Date
- 24 months
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- GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))
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Alternative Name
- GSG2
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Background
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Synonyms: Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase)
Target Description: Histone H3 Associated Protein Kinase is encoded by the gene HASPIN. HASPIN is a member of the protein kinase superfamily, Ser/Thr protein kinase family, and the Haspin subfamily. HASPIN is a serine/threonine - protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. HASPIN may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment, and normal progression through the cell cycle. HASPIN is expressed in the testis, thymus, bone marrow, prostate, intestine, lung, spleen, and lymph node. No diseases were found to be associated with HASPIN.
Gene Name Alternatives: HASPIN GSG2
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Molecular Weight
- 90 kDa
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UniProt
- Q8TF76
Target
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