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GSG2 antibody (AA 1-798)

This anti-GSG2 antibody is a Mouse Monoclonal antibody detecting GSG2 in WB, ICC and IP. Suitable for Human.
Catalog No. ABIN1304694

Quick Overview for GSG2 antibody (AA 1-798) (ABIN1304694)

Target

See all GSG2 Antibodies
GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Reactivity

  • 29
  • 4
  • 4
  • 2
Human

Host

  • 27
  • 6
Mouse

Clonality

  • 28
  • 5
Monoclonal

Conjugate

  • 15
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GSG2 antibody is un-conjugated

Application

  • 16
  • 9
  • 8
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone

N128A-2
  • Binding Specificity

    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-798

    Specificity

    No off-targets reported

    Cross-Reactivity

    Human

    Characteristics

    Description: Our Anti-Haspin/GSG2 mouse monoclonal primary antibody is produced in-house from hybridoma clone N128A/2. It detects human Haspin/GSG2, and is purified by Protein A chromatography. It is great for use in ICC, IP, WB.

    Manufacturer Comment: We produce our Haspin/GSG2 mouse monoclonal primary antibody from hybridoma clone N128A/2. It is great in ICC, IP, WB and is purified by Protein A chromatography.

    Purification

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

    Purity

    > 90% specific antibody

    Immunogen

    Fusion protein amino acids 1-798 (full-length) of human Haspin (accession number Q8TF76)

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

    Storage

    4 °C,-20 °C

    Storage Comment

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    Expiry Date

    24 months
  • Target

    GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

    Alternative Name

    GSG2

    Background

    Synonyms: Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase)

    Target Description: Histone H3 Associated Protein Kinase is encoded by the gene HASPIN. HASPIN is a member of the protein kinase superfamily, Ser/Thr protein kinase family, and the Haspin subfamily. HASPIN is a serine/threonine - protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. HASPIN may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment, and normal progression through the cell cycle. HASPIN is expressed in the testis, thymus, bone marrow, prostate, intestine, lung, spleen, and lymph node. No diseases were found to be associated with HASPIN.

    Gene Name Alternatives: HASPIN GSG2

    Molecular Weight

    90 kDa

    UniProt

    Q8TF76
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