DLG3 antibody (AA 1-120)

Catalog No. ABIN1304942

The Mouse Monoclonal anti-DLG3 antibody has been validated for WB, IHC, ICC and IP. It is suitable to detect DLG3 in samples from Rat.

Quick Overview for DLG3 antibody (AA 1-120) (ABIN1304942)

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLG3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: N19-2

Product Details anti-DLG3 Antibody

Binding Specificity: AA 1-120

Specificity: No off-targets reported for other MAGUK family membersPSD-95, SAP97, Chapsyn-110

Cross-Reactivity: Human, Mouse, Rabbit, Rat

Characteristics:

Description: Our Anti-SAP102 mouse monoclonal primary antibody is produced in-house from hybridoma clone N19/2. It is KO validated, detects human, mouse, and rat SAP102, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our SAP102 mouse monoclonal primary antibody from hybridoma clone N19/2. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Purity: > 90% specific antibody

Immunogen: Fusion protein amino acids 1-120 of rat SAP102 (accession number Q62936) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes:

Dilution Range: IP: 1 μg

Dilution Range: IHC: 1:500

Dilution Range: ICC: 1:500

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 24 months

Target Details for DLG3

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Alternative Name: SAP102

Background:

Synonyms: Disks large homolog 3 (PSD-95/SAP90-related protein 1) (Synapse-associated protein 102) (SAP-102) (SAP102)

Target Description: Synapse-Associated Protein 102, Disks large homolog 3(DLG3) or SAP102 MAGUK scaffold protein is encoded by the gene DLG3. SAP102 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. SAP102 can bind to a number of adhesion molecules and receptors, including NMDA receptors and acts as a scaffold protein to mediate synaptic signaling. This protein plays a role in learning and memory and appears to be required for learning. Mutations in this gene have been associated with X-linked cognitive disability.

Gene Name Alternatives: Dlg3 Dlgh3

Molecular Weight: 105 kDa

UniProt: Q62936