KCNT2 antibody (AA 564-624)

Catalog No. ABIN1304960

The Mouse Monoclonal anti-KCNT2 antibody has been validated for WB, IHC, ICC, IP and IEM. It is suitable to detect KCNT2 in samples from Mouse.

Quick Overview for KCNT2 antibody (AA 564-624) (ABIN1304960)

Target: KCNT2 (Potassium Channel, Subfamily T, Member 2 (KCNT2))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This KCNT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunoelectron Microscopy (IEM)

Clone: N11-33

Product Details anti-KCNT2 Antibody

Binding Specificity: AA 564-624

Specificity: No off-targets reported

Cross-Reactivity: Mouse, Rat, Xenopus laevis

Characteristics:

Description: Our Anti-Slo2.1/Slick K+ channel mouse monoclonal primary antibody is produced in-house from hybridoma clone N11/33. It is KO validated, detects mouse, rat, and Xenopus Slo2.1/Slick K+ channel, and is purified by Protein A chromatography. It is great for use in EM, IHC, ICC, IP, WB.

Manufacturer Comment: We produce our Slo2.1/Slick K+ channel mouse monoclonal primary antibody from hybridoma clone N11/33. It is great in EM, IHC, ICC, IP, WB and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Purity: > 90% specific antibody

Immunogen: Fusion protein amino acids 564-624 of mouse Slo2.1 (accession number XP_920840) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes:

Dilution Range: IP: 40 μg

Dilution Range: IHC: 1:250

Dilution Range: ICC: 1:100

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 24 months

Target Details for KCNT2

Target: KCNT2 (Potassium Channel, Subfamily T, Member 2 (KCNT2))

Alternative Name: Slo2.1

Background:

Synonyms: Potassium channel, subfamily T, member 2

Target Description: Potassium sodium-activated channel subfamily T member 2 is encoded by the gene KCNT2. KCNT2 is a member of the potassium channel family, calcium-activated (TC 1.A.1.3) subfamily, KCa4.2/KCNT2 sub-subfamily. KCNT2 is an outward rectifying potassium channel which produces rapidly activating outward rectifying K+ currents. KCNT2 is expressed in the brain and skin. Diseases associated with KCNT2 include Early Infantile Epileptic Encephalopathy 57 and Bulbar Polio.

Gene Name Alternatives: Kcnt2

Molecular Weight: 140 kDa

NCBI Accession: XP_920840